Tips for cancer

To the Editor Notwithstanding the documented intolerance of guideline-directed medical therapy (GDMT) in the Teachable Moment by Ayoola et al, measured uptitration of medication can mitigate the risk of intolerance of GDMT-related medications in patients with heart failure and transthyretin amyloid cardiomyopathy (ATTR-CM). from JAMA Internal Medicine Online First https://ift.tt/G684PZk

In Reply We appreciate the opportunity to respond to the Letter regarding our Teachable Moment in which Jolobe advocates for guideline-directed medical therapy (GDMT) in transthyretin amyloid cardiomyopathy (ATTR-CM). Although exploring traditional GDMT in this population is laudable, the evidence presented does not substantiate the conclusions, and it risks misapplication in clinical practice. from JAMA Internal Medicine Online First https://ift.tt/871xGIf

This systematic review and meta-analysis identifies reports of systematic reviews that included retracted studies in their meta-analyses, and assesses the impact of these retracted studies on the results. from JAMA Internal Medicine Online First https://ift.tt/ycRjHhb

This cohort study examines whether prenatal use of smoking cessation pharmacotherapies is associated with increased risks of major congenital malformations. from JAMA Internal Medicine Online First https://ift.tt/9GePOgd

This Viewpoint discusses the critical importance of continued funding for the intramural research program in the Department of Veterans Affairs. from JAMA Internal Medicine Online First https://ift.tt/9dslZUK

This cross-sectional study examines plan-level differences between Veteran Medicare Advantage affinity plans and other Medicare Advantage plans and characteristics of their veteran enrollees. from JAMA Health Forum New Online https://ift.tt/6scvjmo

This cohort study evaluates the risks for incident diabetes and hypertension among Hispanic/Latino adults in 4 US cities by levels of acculturation and educational attainment. from JAMA Health Forum New Online https://ift.tt/sGwcXMn

This JAMA Forum discusses the recently formed Make America Healthy Again commission and suggests a few key policies that align with ongoing federal programs and initiatives. from JAMA Health Forum New Online https://ift.tt/5KmO6px

Health Care Policy from JAMA Internal Medicine Online First https://ift.tt/Go5dOfz

Health Care Policy from JAMA Internal Medicine Online First https://ift.tt/gucmG1w

This population-based, cross-sectional study investigates avoidable mortality trends and health care spending in all US states compared with member countries of the European Union and Organisation for Economic Co-operation and Development. from JAMA Internal Medicine Online First https://ift.tt/qkBESRr

This essay discusses improving active shooter trainings for health care professionals to include a focus on prevention, acknowledge the range of gun violence, including suicide, and include support resources for participants. from JAMA Internal Medicine Online First https://ift.tt/5EiTtWI

This Viewpoint discusses the unrealistic standards for error-free decision-making by physicians and how this relates to the evolving landscape of artificial intelligence–assisted health care. from JAMA Health Forum New Online https://ift.tt/RNu2Lpv

This JAMA Forum discusses the budgets for Medicaid and Medicare and the implications of budget changes for the future of these programs. from JAMA Health Forum New Online https://ift.tt/UCMvGpc

This cluster randomized trial assess whether including 2 nudge messages in the electronic health record asking clinicians to document 6-month functional prognosis of critically ill patients and whether a comfort care alternative was offered reduced length of stay compared with usual care. from JAMA Internal Medicine Online First https://ift.tt/QcC4jgK

This cohort study evaluates the association between statin use and the risk of hepatocellular carcinoma and hepatic decompensation in patients with chronic liver disease. from JAMA Internal Medicine Online First https://ift.tt/KlF8z1O

This essay discusses the challenges of coordinating a microtransition for a family member in a skilled nursing facility. from JAMA Internal Medicine Online First https://ift.tt/b8MeGQN

We sincerely thank the 928 peer reviewers who completed manuscript reviews for JAMA Internal Medicine in 2024. from JAMA Internal Medicine Online First https://ift.tt/MNW9hfq

This study compares the cost-effectiveness of 4 antiobesity medications (naltrexone-bupropion, phentermine-topiramate, semaglutide, or tirzepatide) with lifestyle modification vs lifestyle modification alone in US adults. from JAMA Health Forum New Online https://ift.tt/0JG5bNC

Drawing on a growing methods literature in legal epidemiology, this Viewpoint describes difficulties of quantifying health impacts of legal policies and outlines some steps that are key to creating scientifically credible legal data. from JAMA Health Forum New Online https://ift.tt/QulHd7e

This JAMA Forum discusses US health insurance, including the rise and fall of health maintenance organizations, consumer problems with insurance today, and the need for consumer protections. from JAMA Health Forum New Online https://ift.tt/sN4AEil

This nonrandomized clinical trial investigates the association of a streamlined evaluation approach for patients undergoing kidney transplant with waitlisting and transplant likelihood. from JAMA Internal Medicine Online First https://ift.tt/j1oBq7E

This essay describes the author’s experience with the psychological impact for the physician of iatrogenic complications when treating patients. from JAMA Internal Medicine Online First https://ift.tt/z8QSZw6

This Viewpoint discusses population-based payment models as a novel mechanism to provide increased, stable, and predictable funding for health care for unhoused individuals from JAMA Health Forum New Online https://ift.tt/MWHPwND

This cohort study investigates associations of butter and plant-based oil intakes with risk of total and cause-specific mortality among US adults. from JAMA Internal Medicine Online First https://ift.tt/w6gnOBi

This JAMA Forum discusses barriers to state public health efforts, the outlook for public health, and suggestions to help protect the public’s health in the coming years. from JAMA Health Forum New Online https://ift.tt/asRP2Cb

This Viewpoint assesses prescription of medications to treat alcohol use disorder by primary care clinicians. from JAMA Internal Medicine Online First https://ift.tt/ZLgM5Cy