Tolerance of Guideline-Directed Medical Therapy—Reply

In Reply We appreciate the opportunity to respond to the Letter regarding our Teachable Moment in which Jolobe advocates for guideline-directed medical therapy (GDMT) in transthyretin amyloid cardiomyopathy (ATTR-CM). Although exploring traditional GDMT in this population is laudable, the evidence presented does not substantiate the conclusions, and it risks misapplication in clinical practice.

from JAMA Internal Medicine Online First https://ift.tt/871xGIf