Caution in Interpreting Results of CT-Cancer Association Study—Reply

In Reply We thank Hsu et al for their Letter and agree that CT imaging advancements can reduce radiation doses; however, we disagree that we overestimated the doses in our study. Hsu et al suggest our estimates predate widespread deep learning reconstruction algorithm use and AI-driven protocol optimization, claiming these are now standard. Though not without dose reduction potential, their widespread adoption or measurable impact has not been established. The Letter’s references, including Koetzier et al, discuss development, limited availability, and potential, rather than implementation, concluding these techniques need thorough assessment before replacing conventional ones. While promising, photon-counting CT lacks clinical evidence of practical dose reductions.

from JAMA Internal Medicine Online First https://ift.tt/xHPU5pw