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Showing posts from December, 2025

Gestational Diabetes in the US

This cross-sectional study assessed patterns in gestational diabetes rates across 6 primary racial and ethnic groups as well as individual Asian and Hispanic ethnicities in the US from 2016 to 2024. from JAMA Internal Medicine Online First https://ift.tt/M3x8J7L

Metformin Therapy for Patients With COVID-19 Without Obesity

To the Editor We read with great interest the ACTIV-6 study by Bramante et al, which reported that metformin did not significantly shorten the time to sustained recovery among low-risk, predominantly vaccinated, outpatient adults with mild to moderate COVID-19 who were not overweight. While the trial was rigorously designed and contributes important data, several methodological limitations and interpretive concerns warrant further discussion. from JAMA Internal Medicine Online First https://ift.tt/gCNPLbA

Metformin Therapy for Patients With COVID-19 Without Obesity—Reply

In Reply In response to the thoughtful comments by Chang and Jean, we acknowledge that there are limitations related to the design of the ACTIV-6 trial, most of which are noted in the primary publication. We appreciate the opportunity to respond further to these points below. from JAMA Internal Medicine Online First https://ift.tt/Cgb2YsM

Collaborative Care for Opioid Use Disorder and Mental Illness

This randomized clinical trial investigates whether collaborative care, tailored for patients with opioid use disorder and co-occurring depression and/or posttraumatic stress disorder, improves outcomes more so than enhanced usual care. from JAMA Internal Medicine Online First https://ift.tt/SGbjov2

Using Medical Loss Ratio Data to Examine Advance Premium Tax Credits

This economic evaluation examines trends in enrollment, premiums, and advance premium tax credits for insurance plans. from JAMA Health Forum New Online https://ift.tt/ftHxWSQ

Outpatient Emergency Department Use Among Publicly Insured Patients

This cross-sectional study examines emergency department visits from 2008 to 2023 in California. from JAMA Health Forum New Online https://ift.tt/Nb7snxY

Socioeconomic Disparities in Caregiver Burden Among Families of Older Patients With Cancer

This cross-sectional study aims to quantify multidimensional caregiving burden, psychological distress, and economic burden, with a focus on the impact of socioeconomic disparities, among family caregivers of older patients with cancer in China. from JAMA Health Forum New Online https://ift.tt/leGSX24

Hospital–Medicare Advantage Vertical Integration and Cardiopulmonary Care

This cross-sectional study examines associations between level of hospital-Medicare Advantage (MA) vertical integration exposure with care intensity and clinical outcomes among MA enrollees hospitalized for cardiopulmonary disease. from JAMA Health Forum New Online https://ift.tt/YWkmZyM

Burdensome Health Care Spending Over Time in the US

This cohort study assesses burdensome out-of-pocket health care costs over a 4-year period among individuals in the US. from JAMA Internal Medicine Online First https://ift.tt/6eTVkf9

Different Definitions of Developmental Disability and Implications for Outcomes

This cross-sectional study examines different approaches to defining developmental disabilities using data from the 2023 Survey of Income and Program Participation on population prevalence, service utilization, and other related outcomes. from JAMA Health Forum New Online https://ift.tt/0UGKm8p

Prescription for Division—Healing the Growing Gap in Physician Trust

This JAMA Forum discusses the erosion of physician trust after the COVID-19 pandemic and provides short- and long-term suggestions for repairing the patient-physician relationship. from JAMA Health Forum New Online https://ift.tt/TUQYFqp

Air Conditioning in Nursing Homes and Mortality During Extreme Heat

This case-crossover study assesses mortality rates during extreme heat days in nursing homes with air conditioning compared to those without air conditioning. from JAMA Internal Medicine Online First https://ift.tt/SoqYWRL

Intensive Care Unit Admissions Purchased or Delivered by Veterans in the VA Health Care System

This cross-sectional study examines impacts of implementation of the Veterans Affairs MISSION (Maintaining Internal Systems and Strengthening Integrated Outside Networks) Act and the COVID-19 pandemic in critical care delivery for veterans comparing intensive care unit admissions at Veterans Affairs medical centers with community hospitals. from JAMA Health Forum New Online https://ift.tt/4LSNWlm

How AI Will Help Solve Medicine’s Productivity Challenges

This JAMA Forum discusses the potential for artificial intelligence (AI) to improve productivity in medicine and explores the changes needed in regulation and reimbursement to support the effective implementation of medical AI tools. from JAMA Health Forum New Online https://ift.tt/biqaXP9

Magnesium Supplementation and Tachyarrhythmias

This nonrandomized clinical trial evaluates whether giving magnesium supplementation to patients with hypomagnesemia reduces adverse clinical outcomes. from JAMA Internal Medicine Online First https://ift.tt/y5SNt7Q

Public Health for the Post–COVID-19 Public

This Viewpoint proposes 4 principles for a new approach to public health that addresses distrust in the current politicized landscape in the US. from JAMA Health Forum New Online https://ift.tt/O1FZGw6

Rhetoric vs Reality on Immigrants’ Health Care Spending

This JAMA Forum discusses eligibility restrictions for emergency Medicaid coverage, cuts to health care coverage for legal immigrants, and the broader pattern of health care cuts made by the Trump administration and Congressional allies. from JAMA Health Forum New Online https://ift.tt/GiWLnFB

An Unexpected Cause of Hypotension

This Teachable Moment discusses a case of hypotension caused by severe adrenal insufficiency in a man in his 70s. from JAMA Internal Medicine Online First https://ift.tt/o26tqfO